BAIT
PDE4DIP
4732458A06Rik, 9430063L05Rik, C87016, D130016K21Rik, D3Bwg1078e, Usmg4, mKIAA0454
phosphodiesterase 4D interacting protein (myomegalin)
GO Process (1)
GO Function (2)
GO Component (5)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Mus musculus
PREY
PURB
2310015K15Rik, AA114818, Cager-2, D11Bwg0414e, RP23-74L9.2
purine rich element binding protein B
GO Process (7)
GO Function (13)
GO Component (3)
Gene Ontology Biological Process
- apoptotic process [NAS]
- cell differentiation [NAS]
- cell proliferation [NAS]
- negative regulation of transcription from RNA polymerase II promoter [IDA, IGI]
- negative regulation of transcription, DNA-templated [IDA, ISO]
- negative regulation of translation [ISO]
- transcription from RNA polymerase II promoter [IDA]
Gene Ontology Molecular Function- RNA binding [IDA]
- RNA polymerase II regulatory region sequence-specific DNA binding [IDA]
- RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription [IDA]
- SMAD binding [IDA]
- double-stranded DNA binding [IDA]
- mRNA binding [IDA]
- poly(A) RNA binding [ISO]
- protein binding [IPI]
- purine-rich negative regulatory element binding [ISO]
- sequence-specific DNA binding transcription factor activity [IDA]
- single-stranded DNA binding [IDA, ISO]
- transcription factor binding [IPI]
- translation repressor activity, nucleic acid binding [ISO]
- RNA binding [IDA]
- RNA polymerase II regulatory region sequence-specific DNA binding [IDA]
- RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription [IDA]
- SMAD binding [IDA]
- double-stranded DNA binding [IDA]
- mRNA binding [IDA]
- poly(A) RNA binding [ISO]
- protein binding [IPI]
- purine-rich negative regulatory element binding [ISO]
- sequence-specific DNA binding transcription factor activity [IDA]
- single-stranded DNA binding [IDA, ISO]
- transcription factor binding [IPI]
- translation repressor activity, nucleic acid binding [ISO]
Gene Ontology Cellular Component
Mus musculus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.
The postsynaptic density (PSD) contains a collection of scaffold proteins used for assembling synaptic signaling complexes. However, it is not known how the core-scaffold machinery associates in protein-interaction networks or how proteins encoded by genes involved in complex brain disorders are distributed through spatiotemporal protein complexes. Here using immunopurification, proteomics and bioinformatics, we isolated 2,876 proteins across 41 in vivo ... [more]
Nat. Neurosci. Aug. 01, 2017; 20(8);1150-1161 [Pubmed: 28671696]
Throughput
- High Throughput
Additional Notes
- Adult non-postsynaptic density (PSD)
Curated By
- BioGRID