BAIT
PDE4DIP
4732458A06Rik, 9430063L05Rik, C87016, D130016K21Rik, D3Bwg1078e, Usmg4, mKIAA0454
phosphodiesterase 4D interacting protein (myomegalin)
GO Process (1)
GO Function (2)
GO Component (5)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Mus musculus
PREY
TNR
J1-tenascin, TN-R, janusin, restrictin
tenascin R
GO Process (17)
GO Function (2)
GO Component (7)
Gene Ontology Biological Process
- associative learning [IMP]
- extracellular matrix organization [IMP]
- locomotory exploration behavior [IMP]
- long-term synaptic potentiation [IMP]
- negative regulation of axon extension [IDA]
- negative regulation of axon extension involved in regeneration [IMP]
- negative regulation of cell adhesion [ISO]
- negative regulation of cell-cell adhesion [IDA, IMP]
- negative regulation of neuron projection development [IDA]
- negative regulation of synaptic transmission [IMP]
- neuromuscular process controlling balance [IMP]
- neuron cell-cell adhesion [IMP]
- positive regulation of synaptic transmission, glutamatergic [IMP]
- positive regulation of transmission of nerve impulse [IMP]
- regulation of synaptic transmission [IMP]
- synapse organization [IMP]
- telencephalon cell migration [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.
The postsynaptic density (PSD) contains a collection of scaffold proteins used for assembling synaptic signaling complexes. However, it is not known how the core-scaffold machinery associates in protein-interaction networks or how proteins encoded by genes involved in complex brain disorders are distributed through spatiotemporal protein complexes. Here using immunopurification, proteomics and bioinformatics, we isolated 2,876 proteins across 41 in vivo ... [more]
Nat. Neurosci. Aug. 01, 2017; 20(8);1150-1161 [Pubmed: 28671696]
Throughput
- High Throughput
Additional Notes
- Adult non-postsynaptic density (PSD)
Curated By
- BioGRID