BAIT
FANCD2
2410150O07Rik, AU015151, BB137857, FA-D2, FA4, FACD, FAD, FANCD
Fanconi anemia, complementation group D2
GO Process (4)
GO Function (2)
GO Component (5)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
C3
AI255234, ASP, HSE-MSF, Plp
complement component 3
GO Process (15)
GO Function (4)
GO Component (3)
Gene Ontology Biological Process
- blood coagulation [ISO]
- complement activation [IDA, ISO]
- positive regulation of ERK1 and ERK2 cascade [ISO]
- positive regulation of G-protein coupled receptor protein signaling pathway [ISO]
- positive regulation of activation of membrane attack complex [IMP]
- positive regulation of angiogenesis [IMP]
- positive regulation of apoptotic cell clearance [ISO]
- positive regulation of developmental growth [ISO]
- positive regulation of glucose transport [ISO]
- positive regulation of lipid storage [ISO]
- positive regulation of phagocytosis [IMP]
- positive regulation of protein phosphorylation [ISO]
- positive regulation of type IIa hypersensitivity [IMP]
- positive regulation vascular endothelial growth factor production [ISO]
- regulation of triglyceride biosynthetic process [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Fancd2 in vivo interaction network reveals a non-canonical role in mitochondrial function.
Fancd2 is a component of the Fanconi anemia (FA) DNA repair pathway, which is frequently found defective in human cancers. The full repertoire of Fancd2 functions in normal development and tumorigenesis remains to be determined. Here we developed a Flag- and hemagglutinin-tagged Fancd2 knock-in mouse strain that allowed a high throughput mass spectrometry approach to search for Fancd2-binding proteins in ... [more]
Sci Rep Apr. 05, 2017; 7();45626 [Pubmed: 28378742]
Throughput
- High Throughput
Curated By
- BioGRID