BAIT
FANCD2
2410150O07Rik, AU015151, BB137857, FA-D2, FA4, FACD, FAD, FANCD
Fanconi anemia, complementation group D2
GO Process (4)
GO Function (2)
GO Component (5)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
FGB
2510049G14Rik
fibrinogen beta chain
GO Process (13)
GO Function (4)
GO Component (10)
Gene Ontology Biological Process
- cell-matrix adhesion [ISO]
- cellular protein complex assembly [ISO]
- negative regulation of endothelial cell apoptotic process [ISO]
- negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [ISO]
- platelet aggregation [ISO]
- positive regulation of ERK1 and ERK2 cascade [ISO]
- positive regulation of exocytosis [ISO]
- positive regulation of heterotypic cell-cell adhesion [ISO]
- positive regulation of peptide hormone secretion [ISO]
- positive regulation of protein secretion [ISO]
- positive regulation of vasoconstriction [ISO]
- protein polymerization [ISO]
- response to calcium ion [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Fancd2 in vivo interaction network reveals a non-canonical role in mitochondrial function.
Fancd2 is a component of the Fanconi anemia (FA) DNA repair pathway, which is frequently found defective in human cancers. The full repertoire of Fancd2 functions in normal development and tumorigenesis remains to be determined. Here we developed a Flag- and hemagglutinin-tagged Fancd2 knock-in mouse strain that allowed a high throughput mass spectrometry approach to search for Fancd2-binding proteins in ... [more]
Sci Rep Apr. 05, 2017; 7();45626 [Pubmed: 28378742]
Throughput
- High Throughput
Curated By
- BioGRID