BAIT
FANCD2
2410150O07Rik, AU015151, BB137857, FA-D2, FA4, FACD, FAD, FANCD
Fanconi anemia, complementation group D2
GO Process (4)
GO Function (2)
GO Component (5)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
ARF1
RP23-192P17.1
ADP-ribosylation factor 1
GO Process (18)
GO Function (6)
GO Component (9)
Gene Ontology Biological Process
- Golgi to transport vesicle transport [ISO]
- actin filament organization [ISO]
- cellular copper ion homeostasis [ISO]
- dendritic spine organization [ISO]
- long term synaptic depression [ISO]
- positive regulation of ER to Golgi vesicle-mediated transport [ISO]
- positive regulation of calcium ion-dependent exocytosis [ISO]
- positive regulation of dendritic spine development [ISO]
- positive regulation of endocytosis [ISO]
- positive regulation of late endosome to lysosome transport [ISO]
- positive regulation of protein secretion [ISO]
- positive regulation of sodium ion transmembrane transport [ISO]
- protein transport [TAS]
- regulation of Arp2/3 complex-mediated actin nucleation [ISO]
- regulation of receptor internalization [ISO]
- synaptic vesicle budding [ISO]
- very-low-density lipoprotein particle assembly [ISO]
- vesicle-mediated transport [IDA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Fancd2 in vivo interaction network reveals a non-canonical role in mitochondrial function.
Fancd2 is a component of the Fanconi anemia (FA) DNA repair pathway, which is frequently found defective in human cancers. The full repertoire of Fancd2 functions in normal development and tumorigenesis remains to be determined. Here we developed a Flag- and hemagglutinin-tagged Fancd2 knock-in mouse strain that allowed a high throughput mass spectrometry approach to search for Fancd2-binding proteins in ... [more]
Sci Rep Apr. 05, 2017; 7();45626 [Pubmed: 28378742]
Throughput
- High Throughput
Curated By
- BioGRID