BAIT
FANCD2
2410150O07Rik, AU015151, BB137857, FA-D2, FA4, FACD, FAD, FANCD
Fanconi anemia, complementation group D2
GO Process (4)
GO Function (2)
GO Component (5)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
CTNND1
AA409437, AU019353, Catns, Ctnnd, P120, mKIAA0384
catenin (cadherin associated protein), delta 1
GO Process (7)
GO Function (7)
GO Component (15)
Gene Ontology Biological Process
- cell adhesion [IMP]
- epithelial cell differentiation involved in salivary gland development [IMP]
- keratinocyte differentiation [IMP]
- morphogenesis of a polarized epithelium [IMP]
- negative regulation of canonical Wnt signaling pathway [ISO]
- salivary gland morphogenesis [IMP]
- single organismal cell-cell adhesion [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- cell-cell adherens junction [IDA]
- cell-cell junction [ISO]
- cytoplasm [ISO]
- cytosol [ISO]
- dendritic spine [ISO]
- extracellular vesicular exosome [ISO]
- growth cone [ISO]
- lamellipodium [IDA, ISO]
- membrane [IDA]
- midbody [ISO]
- nucleus [ISO]
- plasma membrane [IMP, ISO]
- synapse [ISO]
- tight junction [IDA]
- zonula adherens [ISO]
Mus musculus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Fancd2 in vivo interaction network reveals a non-canonical role in mitochondrial function.
Fancd2 is a component of the Fanconi anemia (FA) DNA repair pathway, which is frequently found defective in human cancers. The full repertoire of Fancd2 functions in normal development and tumorigenesis remains to be determined. Here we developed a Flag- and hemagglutinin-tagged Fancd2 knock-in mouse strain that allowed a high throughput mass spectrometry approach to search for Fancd2-binding proteins in ... [more]
Sci Rep Apr. 05, 2017; 7();45626 [Pubmed: 28378742]
Throughput
- High Throughput
Curated By
- BioGRID