BAIT
FANCD2
2410150O07Rik, AU015151, BB137857, FA-D2, FA4, FACD, FAD, FANCD
Fanconi anemia, complementation group D2
GO Process (4)
GO Function (2)
GO Component (5)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
SLC1A3
AI504299, B430115D02Rik, Eaat1, GLAST, GLAST-1, GLU-T, GluT-1, Gmt1, MGluT1
solute carrier family 1 (glial high affinity glutamate transporter), member 3
GO Process (21)
GO Function (5)
GO Component (11)
Gene Ontology Biological Process
- D-aspartate import [ISO]
- L-glutamate import [IMP, ISO]
- L-glutamate transmembrane transport [IMP, ISO]
- L-glutamate transport [IDA, ISO]
- auditory behavior [IMP]
- cell morphogenesis involved in neuron differentiation [IMP]
- cranial nerve development [IMP]
- gamma-aminobutyric acid biosynthetic process [IMP]
- glutamate biosynthetic process [IMP]
- glutamate metabolic process [IMP]
- malate-aspartate shuttle [ISO]
- neuromuscular process controlling balance [IMP]
- positive regulation of synaptic transmission [IMP]
- response to amino acid [ISO]
- response to antibiotic [IMP]
- response to drug [IMP]
- response to inorganic substance [ISO]
- response to light stimulus [IMP]
- response to wounding [IMP]
- sensory perception of sound [IMP]
- sodium ion transmembrane transport [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Fancd2 in vivo interaction network reveals a non-canonical role in mitochondrial function.
Fancd2 is a component of the Fanconi anemia (FA) DNA repair pathway, which is frequently found defective in human cancers. The full repertoire of Fancd2 functions in normal development and tumorigenesis remains to be determined. Here we developed a Flag- and hemagglutinin-tagged Fancd2 knock-in mouse strain that allowed a high throughput mass spectrometry approach to search for Fancd2-binding proteins in ... [more]
Sci Rep Apr. 05, 2017; 7();45626 [Pubmed: 28378742]
Throughput
- High Throughput
Curated By
- BioGRID