BAIT
FANCD2
2410150O07Rik, AU015151, BB137857, FA-D2, FA4, FACD, FAD, FANCD
Fanconi anemia, complementation group D2
GO Process (4)
GO Function (2)
GO Component (5)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
EPHA4
2900005C20Rik, AI385584, Cek8, Hek8, Sek, Sek1, Tyro1, rb
Eph receptor A4
GO Process (20)
GO Function (8)
GO Component (19)
Gene Ontology Biological Process
- adult walking behavior [IMP]
- axon guidance [IGI, IMP]
- corticospinal tract morphogenesis [IMP]
- ephrin receptor signaling pathway [IMP]
- fasciculation of motor neuron axon [IMP]
- fasciculation of sensory neuron axon [IMP]
- glial cell migration [ISO]
- motor neuron axon guidance [IMP]
- negative regulation of axon regeneration [IMP, ISO]
- peptidyl-tyrosine phosphorylation [IMP, ISO]
- positive regulation of JUN kinase activity [IDA]
- positive regulation of Rho guanyl-nucleotide exchange factor activity [ISO]
- positive regulation of dendrite morphogenesis [ISO]
- protein autophosphorylation [ISO]
- regulation of Rac GTPase activity [IDA]
- regulation of Rap GTPase activity [IMP]
- regulation of Rho GTPase activity [ISO]
- regulation of astrocyte differentiation [IMP]
- regulation of axonogenesis [IMP]
- regulation of dendritic spine morphogenesis [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- Golgi apparatus [ISO]
- axon [IDA]
- axon terminus [ISO]
- axonal growth cone [ISO]
- cell body [ISO]
- cell projection [ISO]
- cell surface [ISO]
- cytoplasm [ISO]
- dendrite [IDA, ISO]
- dendritic spine [ISO]
- early endosome membrane [IDA]
- endoplasmic reticulum [ISO]
- filopodium [ISO]
- integral component of plasma membrane [IDA, ISO]
- mitochondrial outer membrane [ISO]
- neuromuscular junction [ISO]
- perikaryon [ISO]
- plasma membrane [ISO]
- postsynaptic density [ISO]
Mus musculus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Fancd2 in vivo interaction network reveals a non-canonical role in mitochondrial function.
Fancd2 is a component of the Fanconi anemia (FA) DNA repair pathway, which is frequently found defective in human cancers. The full repertoire of Fancd2 functions in normal development and tumorigenesis remains to be determined. Here we developed a Flag- and hemagglutinin-tagged Fancd2 knock-in mouse strain that allowed a high throughput mass spectrometry approach to search for Fancd2-binding proteins in ... [more]
Sci Rep Apr. 05, 2017; 7();45626 [Pubmed: 28378742]
Throughput
- High Throughput
Curated By
- BioGRID