BAIT
FANCD2
2410150O07Rik, AU015151, BB137857, FA-D2, FA4, FACD, FAD, FANCD
Fanconi anemia, complementation group D2
GO Process (4)
GO Function (2)
GO Component (5)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
MYH6
A830009F23Rik, AA517445, Myhc-a, Myhca, alpha-MHC, RP23-171A13.2
myosin, heavy polypeptide 6, cardiac muscle, alpha
GO Process (21)
GO Function (10)
GO Component (9)
Gene Ontology Biological Process
- ATP catabolic process [ISO]
- BMP signaling pathway [IDA]
- actin filament-based movement [IMP]
- adult heart development [IMP, ISO]
- atrial cardiac muscle tissue morphogenesis [ISO]
- canonical Wnt signaling pathway [IDA]
- cardiac muscle fiber development [IMP]
- in utero embryonic development [IMP]
- muscle contraction [ISO]
- muscle filament sliding [ISO]
- myofibril assembly [IMP]
- regulation of ATPase activity [IMP]
- regulation of blood pressure [IMP]
- regulation of heart contraction [IMP]
- regulation of heart growth [IDA]
- regulation of heart rate [IMP, ISO]
- regulation of the force of heart contraction [IMP, ISO]
- sarcomere organization [IMP]
- striated muscle contraction [IMP, ISO]
- ventricular cardiac muscle tissue morphogenesis [ISO]
- visceral muscle development [IMP]
Gene Ontology Molecular Function- ATP binding [ISO]
- ATPase activity [ISO]
- actin-dependent ATPase activity [ISO]
- calcium-dependent ATPase activity [ISO]
- identical protein binding [ISO]
- microfilament motor activity [IMP, ISO]
- protein binding [IPI]
- protein heterodimerization activity [ISO]
- protein homodimerization activity [ISO]
- protein kinase binding [ISO]
- ATP binding [ISO]
- ATPase activity [ISO]
- actin-dependent ATPase activity [ISO]
- calcium-dependent ATPase activity [ISO]
- identical protein binding [ISO]
- microfilament motor activity [IMP, ISO]
- protein binding [IPI]
- protein heterodimerization activity [ISO]
- protein homodimerization activity [ISO]
- protein kinase binding [ISO]
Gene Ontology Cellular Component
Mus musculus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Fancd2 in vivo interaction network reveals a non-canonical role in mitochondrial function.
Fancd2 is a component of the Fanconi anemia (FA) DNA repair pathway, which is frequently found defective in human cancers. The full repertoire of Fancd2 functions in normal development and tumorigenesis remains to be determined. Here we developed a Flag- and hemagglutinin-tagged Fancd2 knock-in mouse strain that allowed a high throughput mass spectrometry approach to search for Fancd2-binding proteins in ... [more]
Sci Rep Apr. 05, 2017; 7();45626 [Pubmed: 28378742]
Throughput
- High Throughput
Curated By
- BioGRID