BAIT
FANCD2
2410150O07Rik, AU015151, BB137857, FA-D2, FA4, FACD, FAD, FANCD
Fanconi anemia, complementation group D2
GO Process (4)
GO Function (2)
GO Component (5)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
CAT
2210418N07, Cas-1, Cas1, Cs-1, RP23-266F3.2
catalase
GO Process (19)
GO Function (9)
GO Component (14)
Gene Ontology Biological Process
- UV protection [ISO]
- aerobic respiration [IMP]
- cholesterol metabolic process [IMP]
- hemoglobin metabolic process [IMP]
- hydrogen peroxide catabolic process [IDA, IMP, ISO]
- kidney development [ISO]
- negative regulation of NF-kappaB transcription factor activity [IDA]
- negative regulation of apoptotic process [ISO]
- osteoblast differentiation [ISO]
- oxidation-reduction process [IDA]
- positive regulation of NF-kappaB transcription factor activity [IDA]
- positive regulation of phosphatidylinositol 3-kinase signaling [IDA]
- protein homotetramerization [ISO]
- protein tetramerization [ISO]
- response to hypoxia [ISO]
- response to oxidative stress [IDA, IMP, ISO]
- response to reactive oxygen species [ISO]
- triglyceride metabolic process [IMP]
- ureteric bud development [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- Golgi apparatus [ISO]
- cytosol [ISO]
- endoplasmic reticulum [ISO]
- extracellular space [ISO]
- extracellular vesicular exosome [ISO]
- focal adhesion [ISO]
- intracellular membrane-bounded organelle [ISO]
- lysosome [ISO]
- membrane [ISO]
- mitochondrial intermembrane space [ISO]
- mitochondrion [IDA]
- peroxisomal membrane [IDA]
- peroxisome [IDA, ISO]
- plasma membrane [ISO]
Mus musculus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Fancd2 in vivo interaction network reveals a non-canonical role in mitochondrial function.
Fancd2 is a component of the Fanconi anemia (FA) DNA repair pathway, which is frequently found defective in human cancers. The full repertoire of Fancd2 functions in normal development and tumorigenesis remains to be determined. Here we developed a Flag- and hemagglutinin-tagged Fancd2 knock-in mouse strain that allowed a high throughput mass spectrometry approach to search for Fancd2-binding proteins in ... [more]
Sci Rep Apr. 05, 2017; 7();45626 [Pubmed: 28378742]
Throughput
- High Throughput
Curated By
- BioGRID