BAIT
FANCD2
2410150O07Rik, AU015151, BB137857, FA-D2, FA4, FACD, FAD, FANCD
Fanconi anemia, complementation group D2
GO Process (4)
GO Function (2)
GO Component (5)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
RAB11A
RAB11A, member RAS oncogene family
GO Process (24)
GO Function (6)
GO Component (19)
Gene Ontology Biological Process
- GTP catabolic process [IBA, ISO]
- Rab protein signal transduction [IBA]
- astral microtubule organization [ISO]
- cytokinesis [ISO]
- establishment of protein localization to membrane [ISO]
- establishment of protein localization to organelle [ISO]
- establishment of vesicle localization [ISO]
- exocytosis [IBA]
- exosomal secretion [ISO]
- intracellular protein transport [IBA]
- melanosome transport [IMP]
- mitotic metaphase plate congression [ISO]
- multivesicular body assembly [ISO]
- neuron projection development [ISO]
- positive regulation of G2/M transition of mitotic cell cycle [ISO]
- positive regulation of axon extension [IMP]
- positive regulation of epithelial cell migration [ISO]
- protein localization to plasma membrane [ISO]
- regulation of long-term neuronal synaptic plasticity [ISO]
- regulation of multivesicular body size [ISO]
- regulation of protein transport [ISO]
- regulation of vesicle-mediated transport [ISO]
- spindle assembly involved in mitosis [ISO]
- vesicle-mediated transport [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- axon [IDA]
- cell [IMP]
- cleavage furrow [ISO]
- cytoplasm [IDA]
- cytoplasmic vesicle [ISO]
- extracellular vesicular exosome [ISO]
- intracellular [IBA]
- kinetochore microtubule [ISO]
- membrane [IDA]
- mitochondrion [IDA]
- multivesicular body [ISO]
- perinuclear region of cytoplasm [IDA]
- phagocytic vesicle [ISO]
- protein complex [ISO]
- recycling endosome [IDA, ISO]
- spindle pole [ISO]
- trans-Golgi network [ISO]
- transport vesicle [ISO]
- vesicle [ISO]
Mus musculus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Fancd2 in vivo interaction network reveals a non-canonical role in mitochondrial function.
Fancd2 is a component of the Fanconi anemia (FA) DNA repair pathway, which is frequently found defective in human cancers. The full repertoire of Fancd2 functions in normal development and tumorigenesis remains to be determined. Here we developed a Flag- and hemagglutinin-tagged Fancd2 knock-in mouse strain that allowed a high throughput mass spectrometry approach to search for Fancd2-binding proteins in ... [more]
Sci Rep Apr. 05, 2017; 7();45626 [Pubmed: 28378742]
Throughput
- High Throughput
Curated By
- BioGRID