BAIT
FANCD2
2410150O07Rik, AU015151, BB137857, FA-D2, FA4, FACD, FAD, FANCD
Fanconi anemia, complementation group D2
GO Process (4)
GO Function (2)
GO Component (5)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
RAB13
0610007N03Rik, B230212B15Rik
RAB13, member RAS oncogene family
GO Process (15)
GO Function (4)
GO Component (19)
Gene Ontology Biological Process
- GTP catabolic process [ISO]
- Rab protein signal transduction [IBA]
- cellular response to insulin stimulus [ISO]
- cortical actin cytoskeleton organization [IBA, ISO]
- endocytic recycling [IMP, ISO]
- endosomal transport [ISO]
- endothelial cell chemotaxis [IMP]
- establishment of Sertoli cell barrier [ISO]
- establishment of protein localization to plasma membrane [ISO]
- intracellular protein transport [TAS]
- neuron projection development [ISO]
- protein kinase A signaling [ISO]
- protein localization to cell leading edge [IMP]
- protein localization to plasma membrane [ISO]
- tight junction assembly [IBA, ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- Golgi apparatus [IDA]
- cell [IMP]
- cell-cell junction [IDA]
- cytoplasm [ISO]
- cytoplasmic membrane-bounded vesicle [TAS]
- cytoplasmic vesicle [ISO]
- endocytic vesicle [IDA, ISO]
- endosome [IBA]
- extracellular vesicular exosome [ISO]
- extrinsic component of plasma membrane [TAS]
- insulin-responsive compartment [ISO]
- intracellular [IMP]
- lamellipodium [IDA]
- lateral plasma membrane [ISO]
- neuron projection [ISO]
- plasma membrane [ISO]
- recycling endosome [ISO]
- tight junction [IDA, ISO]
- trans-Golgi network [ISO]
Mus musculus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Fancd2 in vivo interaction network reveals a non-canonical role in mitochondrial function.
Fancd2 is a component of the Fanconi anemia (FA) DNA repair pathway, which is frequently found defective in human cancers. The full repertoire of Fancd2 functions in normal development and tumorigenesis remains to be determined. Here we developed a Flag- and hemagglutinin-tagged Fancd2 knock-in mouse strain that allowed a high throughput mass spectrometry approach to search for Fancd2-binding proteins in ... [more]
Sci Rep Apr. 05, 2017; 7();45626 [Pubmed: 28378742]
Throughput
- High Throughput
Curated By
- BioGRID