BAIT
FANCD2
2410150O07Rik, AU015151, BB137857, FA-D2, FA4, FACD, FAD, FANCD
Fanconi anemia, complementation group D2
GO Process (4)
GO Function (2)
GO Component (5)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
RPS6KA5
3110005L17Rik, 6330404E13Rik, AI854034, MSK1, MSPK1, RLPK
ribosomal protein S6 kinase, polypeptide 5
GO Process (13)
GO Function (4)
GO Component (3)
Gene Ontology Biological Process
- histone H2A-S1 phosphorylation [ISO]
- histone H3-S10 phosphorylation [ISO, ISS]
- histone H3-S28 phosphorylation [ISO, ISS]
- histone phosphorylation [ISO]
- interleukin-1-mediated signaling pathway [ISO]
- intracellular signal transduction [IDA, ISO]
- negative regulation of transcription, DNA-templated [ISO]
- positive regulation of NF-kappaB transcription factor activity [ISO]
- positive regulation of histone acetylation [ISO]
- positive regulation of histone phosphorylation [ISO]
- positive regulation of transcription from RNA polymerase II promoter [ISO]
- protein phosphorylation [IDA, ISO]
- regulation of transcription, DNA-templated [IDA, ISO]
Gene Ontology Molecular Function
Mus musculus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Fancd2 in vivo interaction network reveals a non-canonical role in mitochondrial function.
Fancd2 is a component of the Fanconi anemia (FA) DNA repair pathway, which is frequently found defective in human cancers. The full repertoire of Fancd2 functions in normal development and tumorigenesis remains to be determined. Here we developed a Flag- and hemagglutinin-tagged Fancd2 knock-in mouse strain that allowed a high throughput mass spectrometry approach to search for Fancd2-binding proteins in ... [more]
Sci Rep Apr. 05, 2017; 7();45626 [Pubmed: 28378742]
Throughput
- High Throughput
Curated By
- BioGRID