BAIT
FANCD2
2410150O07Rik, AU015151, BB137857, FA-D2, FA4, FACD, FAD, FANCD
Fanconi anemia, complementation group D2
GO Process (4)
GO Function (2)
GO Component (5)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
BAG6
2410045D21Rik, AA408914, BAG-6, Bat3, D17H6S52E, G3, Scythe
BCL2-associated athanogene 6
GO Process (17)
GO Function (6)
GO Component (7)
Gene Ontology Biological Process
- antigen processing and presentation of peptide antigen via MHC class I [TAS]
- brain development [IMP]
- embryo development [IMP]
- internal peptidyl-lysine acetylation [ISO]
- intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [ISO]
- intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [IMP]
- kidney development [IMP]
- lung development [IMP]
- negative regulation of apoptotic process [IGI]
- negative regulation of proteasomal ubiquitin-dependent protein catabolic process [IMP]
- negative regulation of proteolysis [IMP]
- protein stabilization [IMP]
- regulation of apoptotic process [IMP]
- spermatogenesis [IMP]
- synaptonemal complex assembly [IMP]
- tail-anchored membrane protein insertion into ER membrane [ISO]
- ubiquitin-dependent protein catabolic process [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Fancd2 in vivo interaction network reveals a non-canonical role in mitochondrial function.
Fancd2 is a component of the Fanconi anemia (FA) DNA repair pathway, which is frequently found defective in human cancers. The full repertoire of Fancd2 functions in normal development and tumorigenesis remains to be determined. Here we developed a Flag- and hemagglutinin-tagged Fancd2 knock-in mouse strain that allowed a high throughput mass spectrometry approach to search for Fancd2-binding proteins in ... [more]
Sci Rep Apr. 05, 2017; 7();45626 [Pubmed: 28378742]
Throughput
- High Throughput
Curated By
- BioGRID