BAIT
FANCD2
2410150O07Rik, AU015151, BB137857, FA-D2, FA4, FACD, FAD, FANCD
Fanconi anemia, complementation group D2
GO Process (4)
GO Function (2)
GO Component (5)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
PKN1
DBK, F730027O18Rik, PAK1, PRK1, Pkn, Prkcl1, Stk3
protein kinase N1
GO Process (15)
GO Function (12)
GO Component (7)
Gene Ontology Biological Process
- B cell apoptotic process [IMP]
- B cell homeostasis [IMP]
- epithelial cell migration [ISO]
- histone H3-T11 phosphorylation [ISO]
- hyperosmotic response [IDA]
- negative regulation of B cell proliferation [IMP]
- negative regulation of protein kinase activity [IMP]
- negative regulation of protein phosphorylation [IMP]
- protein phosphorylation [IMP, ISO]
- regulation of cell motility [ISO]
- regulation of germinal center formation [IMP]
- regulation of immunoglobulin production [IMP]
- regulation of transcription from RNA polymerase II promoter [ISO]
- renal system process [IMP]
- spleen development [IMP]
Gene Ontology Molecular Function- GTP-Rho binding [ISO]
- Rac GTPase binding [ISO]
- androgen receptor binding [ISO]
- chromatin binding [ISO]
- histone binding [ISO]
- histone deacetylase binding [ISO]
- histone kinase activity (H3-T11 specific) [ISO]
- ligand-dependent nuclear receptor transcription coactivator activity [ISO]
- protein binding [IPI]
- protein kinase C binding [ISO]
- protein kinase activity [IMP, ISO]
- protein serine/threonine kinase activity [ISO]
- GTP-Rho binding [ISO]
- Rac GTPase binding [ISO]
- androgen receptor binding [ISO]
- chromatin binding [ISO]
- histone binding [ISO]
- histone deacetylase binding [ISO]
- histone kinase activity (H3-T11 specific) [ISO]
- ligand-dependent nuclear receptor transcription coactivator activity [ISO]
- protein binding [IPI]
- protein kinase C binding [ISO]
- protein kinase activity [IMP, ISO]
- protein serine/threonine kinase activity [ISO]
Gene Ontology Cellular Component
Mus musculus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Fancd2 in vivo interaction network reveals a non-canonical role in mitochondrial function.
Fancd2 is a component of the Fanconi anemia (FA) DNA repair pathway, which is frequently found defective in human cancers. The full repertoire of Fancd2 functions in normal development and tumorigenesis remains to be determined. Here we developed a Flag- and hemagglutinin-tagged Fancd2 knock-in mouse strain that allowed a high throughput mass spectrometry approach to search for Fancd2-binding proteins in ... [more]
Sci Rep Apr. 05, 2017; 7();45626 [Pubmed: 28378742]
Throughput
- High Throughput
Curated By
- BioGRID