BAIT
FANCD2
2410150O07Rik, AU015151, BB137857, FA-D2, FA4, FACD, FAD, FANCD
Fanconi anemia, complementation group D2
GO Process (4)
GO Function (2)
GO Component (5)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
PURB
2310015K15Rik, AA114818, Cager-2, D11Bwg0414e, RP23-74L9.2
purine rich element binding protein B
GO Process (7)
GO Function (13)
GO Component (3)
Gene Ontology Biological Process
- apoptotic process [NAS]
- cell differentiation [NAS]
- cell proliferation [NAS]
- negative regulation of transcription from RNA polymerase II promoter [IDA, IGI]
- negative regulation of transcription, DNA-templated [IDA, ISO]
- negative regulation of translation [ISO]
- transcription from RNA polymerase II promoter [IDA]
Gene Ontology Molecular Function- RNA binding [IDA]
- RNA polymerase II regulatory region sequence-specific DNA binding [IDA]
- RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription [IDA]
- SMAD binding [IDA]
- double-stranded DNA binding [IDA]
- mRNA binding [IDA]
- poly(A) RNA binding [ISO]
- protein binding [IPI]
- purine-rich negative regulatory element binding [ISO]
- sequence-specific DNA binding transcription factor activity [IDA]
- single-stranded DNA binding [IDA, ISO]
- transcription factor binding [IPI]
- translation repressor activity, nucleic acid binding [ISO]
- RNA binding [IDA]
- RNA polymerase II regulatory region sequence-specific DNA binding [IDA]
- RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription [IDA]
- SMAD binding [IDA]
- double-stranded DNA binding [IDA]
- mRNA binding [IDA]
- poly(A) RNA binding [ISO]
- protein binding [IPI]
- purine-rich negative regulatory element binding [ISO]
- sequence-specific DNA binding transcription factor activity [IDA]
- single-stranded DNA binding [IDA, ISO]
- transcription factor binding [IPI]
- translation repressor activity, nucleic acid binding [ISO]
Gene Ontology Cellular Component
Mus musculus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Fancd2 in vivo interaction network reveals a non-canonical role in mitochondrial function.
Fancd2 is a component of the Fanconi anemia (FA) DNA repair pathway, which is frequently found defective in human cancers. The full repertoire of Fancd2 functions in normal development and tumorigenesis remains to be determined. Here we developed a Flag- and hemagglutinin-tagged Fancd2 knock-in mouse strain that allowed a high throughput mass spectrometry approach to search for Fancd2-binding proteins in ... [more]
Sci Rep Apr. 05, 2017; 7();45626 [Pubmed: 28378742]
Throughput
- High Throughput
Curated By
- BioGRID