FOXF1
Gene Ontology Biological Process
- blood vessel development [ISO]
- branching involved in open tracheal system development [ISO]
- cardiac left ventricle morphogenesis [ISO]
- cellular response to cytokine stimulus [IDA]
- cellular response to organic cyclic compound [IMP]
- detection of wounding [IMP]
- determination of left/right symmetry [IMP]
- digestive tract development [ISO]
- ductus arteriosus closure [ISO]
- embryonic digestive tract development [IGI]
- embryonic digestive tract morphogenesis [ISO]
- embryonic ectodermal digestive tract morphogenesis [ISO]
- embryonic foregut morphogenesis [IMP]
- endocardial cushion development [ISO]
- epithelial cell differentiation involved in mammary gland alveolus development [IGI]
- epithelial tube branching involved in lung morphogenesis [IMP]
- establishment of epithelial cell apical/basal polarity [IGI]
- extracellular matrix organization [IGI]
- heart development [ISO]
- in utero embryonic development [IMP, ISO]
- lateral mesodermal cell differentiation [IMP]
- lung alveolus development [IMP]
- lung development [IMP, ISO]
- lung lobe morphogenesis [IMP]
- lung morphogenesis [IMP]
- lung vasculature development [ISO]
- mesenchyme migration [IMP]
- mesoderm development [IGI, IMP]
- midgut development [ISO]
- morphogenesis of a branching structure [ISO]
- negative regulation of inflammatory response [IMP]
- negative regulation of mast cell degranulation [IMP]
- negative regulation of transcription from RNA polymerase II promoter [IMP]
- organ morphogenesis [IMP]
- pancreas development [ISO]
- positive regulation of cell migration [IMP]
- positive regulation of cell-substrate adhesion [IMP]
- positive regulation of mesenchymal cell proliferation [IMP]
- positive regulation of transcription from RNA polymerase II promoter [IDA, IMP, ISO]
- positive regulation of transcription, DNA-templated [ISO]
- regulation of smooth muscle cell differentiation [IGI, IMP]
- regulation of transcription from RNA polymerase II promoter [IBA]
- renal system development [ISO]
- respiratory tube development [ISO]
- right lung morphogenesis [IMP]
- single organismal cell-cell adhesion [IMP]
- smooth muscle cell differentiation [IMP]
- smoothened signaling pathway [IDA]
- somitogenesis [IMP]
- trachea development [IMP]
- transcription from RNA polymerase II promoter [IBA]
- ureter development [ISO]
- vasculogenesis [IMP]
- venous blood vessel development [ISO]
Gene Ontology Molecular Function- DNA binding [IDA, ISO]
- RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity [IBA]
- RNA polymerase II regulatory region sequence-specific DNA binding [ISO]
- RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription [ISO]
- transcription regulatory region DNA binding [IDA]
- DNA binding [IDA, ISO]
- RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity [IBA]
- RNA polymerase II regulatory region sequence-specific DNA binding [ISO]
- RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription [ISO]
- transcription regulatory region DNA binding [IDA]
FANCD2
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Affinity Capture-Western
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins.
Publication
Forkhead transcription factor FoxF1 interacts with Fanconi anemia protein complexes to promote DNA damage response.
Forkhead box F1 (Foxf1) transcription factor is an important regulator of embryonic development but its role in tumor cells remains incompletely understood. While 16 proteins were characterized in Fanconi anemia (FA) core complex, its interactions with cellular transcriptional machinery remain poorly characterized. Here, we identified FoxF1 protein as a novel interacting partner of the FA complex proteins. Using multiple human ... [more]
Throughput
- Low Throughput
Curated By
- BioGRID