BAIT
PDE4DIP
4732458A06Rik, 9430063L05Rik, C87016, D130016K21Rik, D3Bwg1078e, Usmg4, mKIAA0454
phosphodiesterase 4D interacting protein (myomegalin)
GO Process (1)
GO Function (2)
GO Component (5)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Mus musculus
PREY
PRKCI
2310021H13Rik, AI427505, PKClambda, Pkci, Pkcl, Prkcl, aPKClambda, mKIAA4165
protein kinase C, iota
GO Process (19)
GO Function (6)
GO Component (14)
Gene Ontology Biological Process
- Golgi vesicle budding [ISO]
- actin filament organization [IMP]
- cell migration [ISO]
- cell-cell junction organization [ISO]
- cellular protein localization [ISO]
- cellular response to insulin stimulus [IMP, ISO]
- establishment of apical/basal cell polarity [IMP]
- eye photoreceptor cell development [IMP]
- negative regulation of glial cell apoptotic process [ISO]
- negative regulation of neuron apoptotic process [ISO]
- positive regulation of NF-kappaB transcription factor activity [ISO]
- positive regulation of endothelial cell apoptotic process [ISO]
- positive regulation of establishment of protein localization to plasma membrane [IMP]
- positive regulation of glial cell proliferation [ISO]
- positive regulation of glucose import [IMP]
- positive regulation of neuron projection development [ISO]
- protein phosphorylation [IDA, ISO]
- response to interleukin-1 [ISO]
- response to peptide hormone [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- Golgi membrane [ISO]
- Schmidt-Lanterman incisure [IDA]
- apical part of cell [IDA]
- apical plasma membrane [IDA]
- cell leading edge [ISO]
- cytoplasm [IDA, ISO]
- cytosol [ISO]
- extracellular vesicular exosome [ISO]
- intercellular bridge [ISO]
- microtubule cytoskeleton [ISO]
- nucleus [IDA, ISO]
- plasma membrane [ISO]
- protein complex [ISO]
- tight junction [ISO]
Mus musculus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.
The postsynaptic density (PSD) contains a collection of scaffold proteins used for assembling synaptic signaling complexes. However, it is not known how the core-scaffold machinery associates in protein-interaction networks or how proteins encoded by genes involved in complex brain disorders are distributed through spatiotemporal protein complexes. Here using immunopurification, proteomics and bioinformatics, we isolated 2,876 proteins across 41 in vivo ... [more]
Nat. Neurosci. Aug. 01, 2017; 20(8);1150-1161 [Pubmed: 28671696]
Throughput
- High Throughput
Additional Notes
- e14
Curated By
- BioGRID