BAIT
PEX5L
1700016J08Rik, PXR2, Pex2, TRIP8b
peroxisomal biogenesis factor 5-like
GO Process (9)
GO Function (6)
GO Component (8)
Gene Ontology Biological Process
- cation transmembrane transport [ISO]
- cation transport [ISO]
- maintenance of protein location [IDA]
- positive regulation of corticotropin secretion [ISO]
- protein import into peroxisome matrix [IBA]
- protein import into peroxisome matrix, docking [IBA]
- regulated secretory pathway [ISO]
- regulation of cAMP-mediated signaling [ISO]
- regulation of membrane potential [IDA, IGI]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
PARD3
AA960621, AI256638, ASIP, D8Ertd580e, PAR-3, Par3, Pard3a
par-3 family cell polarity regulator
GO Process (14)
GO Function (6)
GO Component (16)
Gene Ontology Biological Process
- apical constriction [IGI]
- centrosome localization [IMP]
- establishment of epithelial cell polarity [ISO]
- establishment or maintenance of cell polarity [TAS]
- microtubule cytoskeleton organization [IMP]
- myelination in peripheral nervous system [IMP]
- negative regulation of peptidyl-threonine phosphorylation [IMP]
- positive regulation of myelination [IMP]
- protein targeting to membrane [ISO]
- regulation of actin filament-based process [IGI]
- regulation of cellular localization [ISO]
- single organismal cell-cell adhesion [IC]
- tight junction assembly [ISO]
- wound healing, spreading of cells [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- Schmidt-Lanterman incisure [IDA]
- adherens junction [IDA]
- apical part of cell [IDA]
- axonal growth cone [ISO]
- cell cortex [IDA]
- cell junction [IDA, ISO]
- cell-cell adherens junction [IDA]
- cell-cell junction [IDA, ISO]
- cytoplasm [IDA]
- internode region of axon [IDA]
- intracellular [ISO]
- lateral loop [IDA]
- neuronal cell body [ISO]
- protein complex [IDA, ISO]
- spindle [IDA]
- tight junction [IDA, ISO]
Mus musculus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.
The postsynaptic density (PSD) contains a collection of scaffold proteins used for assembling synaptic signaling complexes. However, it is not known how the core-scaffold machinery associates in protein-interaction networks or how proteins encoded by genes involved in complex brain disorders are distributed through spatiotemporal protein complexes. Here using immunopurification, proteomics and bioinformatics, we isolated 2,876 proteins across 41 in vivo ... [more]
Nat. Neurosci. Aug. 01, 2017; 20(8);1150-1161 [Pubmed: 28671696]
Throughput
- High Throughput
Additional Notes
- Adult non-postsynaptic density (PSD)
Curated By
- BioGRID