BAIT
TNIK
1500031A17Rik, 4831440I19Rik, AI451411, C530008O15Rik, C630040K21Rik
TRAF2 and NCK interacting kinase
GO Process (9)
GO Function (3)
GO Component (7)
Gene Ontology Biological Process
- actin cytoskeleton reorganization [ISO]
- activation of JNKK activity [ISO]
- cytoskeleton organization [ISO]
- intracellular signal transduction [IBA, ISO]
- protein autophosphorylation [ISO]
- protein phosphorylation [IBA, ISO]
- regulation of dendrite morphogenesis [ISO]
- response to stress [IBA]
- signal transduction by phosphorylation [IBA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
BCL11B
9130430L19Rik, AI604821, B630002E05Rik, BCL-11B, Ctip2, Rit1
B cell leukemia/lymphoma 11B
GO Process (24)
GO Function (4)
GO Component (3)
Gene Ontology Biological Process
- T cell differentiation in thymus [IMP]
- T cell receptor V(D)J recombination [IMP]
- alpha-beta T cell differentiation [IMP]
- axonogenesis [IMP]
- central nervous system neuron differentiation [IGI]
- commitment of neuronal cell to specific neuron type in forebrain [IGI]
- epithelial cell morphogenesis [IMP]
- keratinocyte development [IMP]
- negative regulation of apoptotic process [IMP]
- negative regulation of cell proliferation [IDA]
- odontogenesis of dentin-containing tooth [IMP]
- olfactory bulb axon guidance [IMP]
- positive T cell selection [IMP]
- positive regulation of transcription from RNA polymerase II promoter [IDA, IGI, IMP, ISO]
- post-embryonic camera-type eye development [IMP]
- post-embryonic development [IMP]
- regulation of gene expression [IMP]
- regulation of keratinocyte proliferation [IMP]
- regulation of lipid metabolic process [IMP]
- regulation of neuron differentiation [IMP]
- skin development [IMP]
- striatal medium spiny neuron differentiation [IMP]
- thymus development [IMP]
- transcription from RNA polymerase II promoter [IDA]
Gene Ontology Molecular Function- RNA polymerase II core promoter proximal region sequence-specific DNA binding [IDA]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription [IDA]
- protein binding [IPI]
- sequence-specific DNA binding [IDA]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding [IDA]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription [IDA]
- protein binding [IPI]
- sequence-specific DNA binding [IDA]
Gene Ontology Cellular Component
Mus musculus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.
The postsynaptic density (PSD) contains a collection of scaffold proteins used for assembling synaptic signaling complexes. However, it is not known how the core-scaffold machinery associates in protein-interaction networks or how proteins encoded by genes involved in complex brain disorders are distributed through spatiotemporal protein complexes. Here using immunopurification, proteomics and bioinformatics, we isolated 2,876 proteins across 41 in vivo ... [more]
Nat. Neurosci. Aug. 01, 2017; 20(8);1150-1161 [Pubmed: 28671696]
Throughput
- High Throughput
Additional Notes
- e14
Curated By
- BioGRID