BAIT
TNIK
1500031A17Rik, 4831440I19Rik, AI451411, C530008O15Rik, C630040K21Rik
TRAF2 and NCK interacting kinase
GO Process (9)
GO Function (3)
GO Component (7)
Gene Ontology Biological Process
- actin cytoskeleton reorganization [ISO]
- activation of JNKK activity [ISO]
- cytoskeleton organization [ISO]
- intracellular signal transduction [IBA, ISO]
- protein autophosphorylation [ISO]
- protein phosphorylation [IBA, ISO]
- regulation of dendrite morphogenesis [ISO]
- response to stress [IBA]
- signal transduction by phosphorylation [IBA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
DDX3X
D1Pas1-rs2, Ddx3, Fin14, RP23-158L19.4
DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3, X-linked
GO Process (27)
GO Function (14)
GO Component (6)
Gene Ontology Biological Process
- ATP catabolic process [ISO]
- DNA duplex unwinding [ISO]
- RNA secondary structure unwinding [ISO]
- cellular response to arsenic-containing substance [ISO]
- cellular response to osmotic stress [ISO]
- chromosome segregation [ISO]
- extrinsic apoptotic signaling pathway via death domain receptors [ISO]
- innate immune response [ISO]
- intracellular signal transduction [ISO]
- intrinsic apoptotic signaling pathway [ISO]
- mature ribosome assembly [ISO]
- negative regulation of apoptotic process [ISO]
- negative regulation of cell growth [ISO]
- negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [ISO]
- negative regulation of intrinsic apoptotic signaling pathway [ISO]
- negative regulation of protein complex assembly [ISO]
- negative regulation of translation [ISO]
- positive regulation of G1/S transition of mitotic cell cycle [ISO]
- positive regulation of apoptotic process [ISO]
- positive regulation of cell growth [ISO]
- positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [ISO]
- positive regulation of transcription from RNA polymerase II promoter [ISO]
- positive regulation of translation [ISO]
- positive regulation of translational initiation [ISO]
- positive regulation of viral genome replication [ISO]
- response to virus [ISO]
- stress granule assembly [ISO]
Gene Ontology Molecular Function- ATP-dependent DNA helicase activity [ISO]
- ATP-dependent RNA helicase activity [ISO]
- ATPase activity [ISO]
- DNA binding [ISO]
- RNA binding [ISO]
- RNA stem-loop binding [ISO]
- eukaryotic initiation factor 4E binding [ISO]
- mRNA 5'-UTR binding [ISO]
- poly(A) RNA binding [ISO]
- poly(A) binding [ISO]
- protein binding [IPI]
- ribosomal small subunit binding [ISO]
- transcription factor binding [ISO]
- translation initiation factor binding [ISO]
- ATP-dependent DNA helicase activity [ISO]
- ATP-dependent RNA helicase activity [ISO]
- ATPase activity [ISO]
- DNA binding [ISO]
- RNA binding [ISO]
- RNA stem-loop binding [ISO]
- eukaryotic initiation factor 4E binding [ISO]
- mRNA 5'-UTR binding [ISO]
- poly(A) RNA binding [ISO]
- poly(A) binding [ISO]
- protein binding [IPI]
- ribosomal small subunit binding [ISO]
- transcription factor binding [ISO]
- translation initiation factor binding [ISO]
Gene Ontology Cellular Component
Mus musculus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.
The postsynaptic density (PSD) contains a collection of scaffold proteins used for assembling synaptic signaling complexes. However, it is not known how the core-scaffold machinery associates in protein-interaction networks or how proteins encoded by genes involved in complex brain disorders are distributed through spatiotemporal protein complexes. Here using immunopurification, proteomics and bioinformatics, we isolated 2,876 proteins across 41 in vivo ... [more]
Nat. Neurosci. Aug. 01, 2017; 20(8);1150-1161 [Pubmed: 28671696]
Throughput
- High Throughput
Additional Notes
- e14
Curated By
- BioGRID