BAIT
TNIK
1500031A17Rik, 4831440I19Rik, AI451411, C530008O15Rik, C630040K21Rik
TRAF2 and NCK interacting kinase
GO Process (9)
GO Function (3)
GO Component (7)
Gene Ontology Biological Process
- actin cytoskeleton reorganization [ISO]
- activation of JNKK activity [ISO]
- cytoskeleton organization [ISO]
- intracellular signal transduction [IBA, ISO]
- protein autophosphorylation [ISO]
- protein phosphorylation [IBA, ISO]
- regulation of dendrite morphogenesis [ISO]
- response to stress [IBA]
- signal transduction by phosphorylation [IBA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
NCOR2
N-CoR, SMRT, SMRTe
nuclear receptor co-repressor 2
GO Process (13)
GO Function (14)
GO Component (8)
Gene Ontology Biological Process
- Type I pneumocyte differentiation [IGI, IMP]
- cell proliferation in forebrain [IMP]
- forebrain development [IMP]
- glucose homeostasis [IMP]
- heart morphogenesis [IGI, IMP]
- in utero embryonic development [IMP]
- negative regulation of fat cell differentiation [IMP]
- negative regulation of transcription from RNA polymerase II promoter [IDA, IGI, IMP, ISO]
- negative regulation of transcription, DNA-templated [IDA, IMP]
- positive regulation of protein deacetylation [IDA]
- regulation of cellular ketone metabolic process by negative regulation of transcription from RNA polymerase II promoter [ISO]
- telencephalon development [IMP]
- white fat cell differentiation [IMP]
Gene Ontology Molecular Function- DNA binding [IDA]
- Notch binding [ISO]
- RNA polymerase II regulatory region DNA binding [ISO]
- chromatin binding [IDA, ISO]
- glucocorticoid receptor binding [ISO]
- histone deacetylase binding [ISO]
- ligand-dependent nuclear receptor binding [ISO]
- protein N-terminus binding [ISO]
- protein binding [IPI]
- protein complex binding [ISO]
- retinoic acid receptor binding [ISO]
- retinoid X receptor binding [ISO]
- sequence-specific DNA binding [IDA]
- transcription corepressor activity [IDA, IGI, IMP, ISO]
- DNA binding [IDA]
- Notch binding [ISO]
- RNA polymerase II regulatory region DNA binding [ISO]
- chromatin binding [IDA, ISO]
- glucocorticoid receptor binding [ISO]
- histone deacetylase binding [ISO]
- ligand-dependent nuclear receptor binding [ISO]
- protein N-terminus binding [ISO]
- protein binding [IPI]
- protein complex binding [ISO]
- retinoic acid receptor binding [ISO]
- retinoid X receptor binding [ISO]
- sequence-specific DNA binding [IDA]
- transcription corepressor activity [IDA, IGI, IMP, ISO]
Gene Ontology Cellular Component
Mus musculus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.
The postsynaptic density (PSD) contains a collection of scaffold proteins used for assembling synaptic signaling complexes. However, it is not known how the core-scaffold machinery associates in protein-interaction networks or how proteins encoded by genes involved in complex brain disorders are distributed through spatiotemporal protein complexes. Here using immunopurification, proteomics and bioinformatics, we isolated 2,876 proteins across 41 in vivo ... [more]
Nat. Neurosci. Aug. 01, 2017; 20(8);1150-1161 [Pubmed: 28671696]
Throughput
- High Throughput
Additional Notes
- e14
Curated By
- BioGRID