BAIT
GABRA1
Gabra-1
gamma-aminobutyric acid (GABA) A receptor, subunit alpha 1
GO Process (2)
GO Function (3)
GO Component (3)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
NLGN2
NL2, RP23-422L16.24
neuroligin 2
GO Process (23)
GO Function (5)
GO Component (6)
Gene Ontology Biological Process
- gephyrin clustering [IDA]
- jump response [ISO]
- locomotory exploration behavior [IMP]
- neuromuscular process controlling balance [IMP]
- neuron cell-cell adhesion [IBA, ISO]
- positive regulation of excitatory postsynaptic membrane potential [IMP]
- positive regulation of inhibitory postsynaptic membrane potential [IMP, ISO]
- positive regulation of synapse assembly [ISO]
- positive regulation of synaptic transmission, GABAergic [IMP]
- positive regulation of synaptic transmission, glutamatergic [IMP]
- postsynaptic density protein 95 clustering [IDA]
- postsynaptic membrane assembly [IDA]
- presynaptic membrane assembly [IDA, IMP, ISO]
- protein localization to synapse [IDA]
- regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity [IMP]
- regulation of respiratory gaseous exchange by neurological system process [IGI]
- regulation of synaptic transmission [IGI]
- sensory perception of pain [IMP]
- social behavior [ISO]
- synapse assembly [ISO]
- synapse organization [ISO]
- terminal button organization [ISO]
- thigmotaxis [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
The biochemical anatomy of cortical inhibitory synapses.
Classical electron microscopic studies of the mammalian brain revealed two major classes of synapses, distinguished by the presence of a large postsynaptic density (PSD) exclusively at type 1, excitatory synapses. Biochemical studies of the PSD have established the paradigm of the synapse as a complex signal-processing machine that controls synaptic plasticity. We report here the results of a proteomic analysis ... [more]
PLoS ONE Jul. 07, 2012; 7(6);e39572 [Pubmed: 22768092]
Throughput
- Low Throughput
Curated By
- BioGRID