GABRA1
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
NRXN1
Gene Ontology Biological Process
- adult behavior [IMP, ISO]
- gephyrin clustering [IDA]
- learning [IMP, ISO]
- neuroligin clustering [IDA]
- neuromuscular process controlling balance [IMP]
- neurotransmitter secretion [IGI, TAS]
- positive regulation of excitatory postsynaptic membrane potential [IMP]
- positive regulation of synapse assembly [IGI]
- positive regulation of synapse maturation [IDA]
- positive regulation of synaptic transmission, glutamatergic [IMP]
- postsynaptic density protein 95 clustering [IDA]
- postsynaptic membrane assembly [IDA]
- prepulse inhibition [IMP]
- protein heterotetramerization [ISO]
- regulation of grooming behavior [IMP]
- regulation of insulin secretion involved in cellular response to glucose stimulus [IMP]
- social behavior [ISO]
- synapse assembly [IGI]
- synaptic transmission [IGI]
- vesicle docking involved in exocytosis [ISO]
- vocal learning [ISO]
- vocalization behavior [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
The biochemical anatomy of cortical inhibitory synapses.
Classical electron microscopic studies of the mammalian brain revealed two major classes of synapses, distinguished by the presence of a large postsynaptic density (PSD) exclusively at type 1, excitatory synapses. Biochemical studies of the PSD have established the paradigm of the synapse as a complex signal-processing machine that controls synaptic plasticity. We report here the results of a proteomic analysis ... [more]
Throughput
- Low Throughput
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| NRXN1 GABRA1 | Proximity Label-MS Proximity Label-MS An interaction is inferred when a bait-enzyme fusion protein selectively modifies a vicinal protein with a diffusible reactive product, followed by affinity capture of the modified protein and identification by mass spectrometric methods. | High | 0.4451 | BioGRID | 3499223 |
Curated By
- BioGRID