BAIT
JADE1
PHF17
jade family PHD finger 1
GO Process (11)
GO Function (2)
GO Component (6)
Gene Ontology Biological Process
- apoptotic process [NAS]
- chromatin organization [TAS]
- histone H3 acetylation [IDA]
- histone H4-K12 acetylation [IDA]
- histone H4-K16 acetylation [IDA]
- histone H4-K5 acetylation [IDA]
- histone H4-K8 acetylation [IDA]
- negative regulation of G1/S transition of mitotic cell cycle [IDA]
- negative regulation of cell growth [NAS]
- positive regulation of transcription from RNA polymerase II promoter [IDA]
- response to stress [NAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
CD3EAP
1190028F09, 2610103M17Rik, ASE-1, Ase1, CAST, PAF49
CD3E antigen, epsilon polypeptide associated protein
GO Process (1)
GO Function (2)
GO Component (5)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Mus musculus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Jade-1S phosphorylation induced by CK1α contributes to cell cycle progression.
The PHD zinc finger protein Jade-1S is a component of the HBO1 histone acetyltransferase complex and binds chromatin in a cell cycle-dependent manner. Jade-1S also acts as an E3 ubiquitin ligase for the canonical Wnt effector protein β-catenin and is influenced by CK1α-mediated phosphorylation. To further elucidate the functional impact of this phosphorylation, we used a stable, low-level expression system ... [more]
Cell Cycle Feb. 27, 2016; 15(8);1034-45 [Pubmed: 26919559]
Throughput
- High Throughput
Curated By
- BioGRID