BAIT
JADE1
PHF17
jade family PHD finger 1
GO Process (11)
GO Function (2)
GO Component (6)
Gene Ontology Biological Process
- apoptotic process [NAS]
- chromatin organization [TAS]
- histone H3 acetylation [IDA]
- histone H4-K12 acetylation [IDA]
- histone H4-K16 acetylation [IDA]
- histone H4-K5 acetylation [IDA]
- histone H4-K8 acetylation [IDA]
- negative regulation of G1/S transition of mitotic cell cycle [IDA]
- negative regulation of cell growth [NAS]
- positive regulation of transcription from RNA polymerase II promoter [IDA]
- response to stress [NAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
GATAD2B
AL118180, C430014D17Rik, P66beta, mKIAA1150
GATA zinc finger domain containing 2B
GO Process (1)
GO Function (4)
GO Component (3)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Jade-1S phosphorylation induced by CK1α contributes to cell cycle progression.
The PHD zinc finger protein Jade-1S is a component of the HBO1 histone acetyltransferase complex and binds chromatin in a cell cycle-dependent manner. Jade-1S also acts as an E3 ubiquitin ligase for the canonical Wnt effector protein β-catenin and is influenced by CK1α-mediated phosphorylation. To further elucidate the functional impact of this phosphorylation, we used a stable, low-level expression system ... [more]
Cell Cycle Feb. 27, 2016; 15(8);1034-45 [Pubmed: 26919559]
Throughput
- High Throughput
Curated By
- BioGRID