BAIT
LGALS8
Gal-8, PCTA-1, PCTA1, Po66-CBP, RP11-385F5.1
lectin, galactoside-binding, soluble, 8
GO Process (0)
GO Function (1)
GO Component (3)
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
TRIM22
GPSTAF50, RNF94, STAF50
tripartite motif containing 22
GO Process (8)
GO Function (2)
GO Component (3)
Gene Ontology Biological Process
- immune response [TAS]
- negative regulation of nucleic acid-templated transcription [TAS]
- positive regulation of I-kappaB kinase/NF-kappaB signaling [IDA]
- positive regulation of NF-kappaB transcription factor activity [IDA]
- positive regulation of sequence-specific DNA binding transcription factor activity [IDA]
- protein trimerization [IDA]
- regulation of transcription, DNA-templated [TAS]
- response to virus [TAS]
Gene Ontology Molecular Function
Homo sapiens
Reconstituted Complex
An interaction is detected between purified proteins in vitro.
Publication
TRIMs and Galectins Globally Cooperate and TRIM16 and Galectin-3 Co-direct Autophagy in Endomembrane Damage Homeostasis.
Selective autophagy performs an array of tasks to maintain intracellular homeostasis, sterility, and organellar and cellular functionality. The fidelity of these processes depends on precise target recognition and limited activation of the autophagy apparatus in a localized fashion. Here we describe cooperation in such processes between the TRIM family and Galectin family of proteins. TRIMs, which are E3 ubiquitin ligases, displayed ... [more]
Dev. Cell Oct. 10, 2016; 39(1);13-27 [Pubmed: 27693506]
Throughput
- Low Throughput
Curated By
- BioGRID