TRIM16
Gene Ontology Biological Process
- histone H3 acetylation [IDA]
- histone H4 acetylation [IDA]
- positive regulation of interleukin-1 beta secretion [IMP]
- positive regulation of keratinocyte differentiation [IDA]
- positive regulation of retinoic acid receptor signaling pathway [IDA]
- positive regulation of transcription, DNA-templated [IDA]
- response to growth hormone [IDA]
- response to organophosphorus [IEP]
- response to retinoic acid [IEP]
Gene Ontology Molecular Function
CUL5
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Affinity Capture-Western
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins.
Publication
TRIMs and Galectins Globally Cooperate and TRIM16 and Galectin-3 Co-direct Autophagy in Endomembrane Damage Homeostasis.
Selective autophagy performs an array of tasks to maintain intracellular homeostasis, sterility, and organellar and cellular functionality. The fidelity of these processes depends on precise target recognition and limited activation of the autophagy apparatus in a localized fashion. Here we describe cooperation in such processes between the TRIM family and Galectin family of proteins. TRIMs, which are E3 ubiquitin ligases, displayed ... [more]
Throughput
- Low Throughput
Curated By
- BioGRID