BAIT
APITD1
CENP-S, CENPS, FAAP16, MHF1
apoptosis-inducing, TAF9-like domain 1
GO Process (6)
GO Function (4)
GO Component (3)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
The histone-fold complex MHF is remodeled by FANCM to recognize branched DNA and protect genome stability.
Histone-fold proteins typically assemble in multiprotein complexes to bind duplex DNA. However, one histone-fold complex, MHF, associates with Fanconi anemia (FA) protein FANCM to form a branched DNA remodeling complex that senses and repairs stalled replication forks and activates FA DNA damage response network. How the FANCM-MHF complex recognizes branched DNA is unclear. Here, we solved the crystal structure of ... [more]
Cell Res. May. 01, 2014; 24(5);560-75 [Pubmed: 24699063]
Throughput
- Low Throughput
Curated By
- BioGRID