BAIT

LASP1

Lasp-1, MLN50
LIM and SH3 protein 1
GO Process (2)
GO Function (3)
GO Component (3)

Gene Ontology Biological Process

Gene Ontology Molecular Function

Gene Ontology Cellular Component

Homo sapiens
PREY

G3BP2

GTPase activating protein (SH3 domain) binding protein 2
GO Process (2)
GO Function (2)
GO Component (1)

Gene Ontology Biological Process

Gene Ontology Molecular Function

Gene Ontology Cellular Component

Homo sapiens

Affinity Capture-MS

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.

Publication

LASP-1: a nuclear hub for the UHRF1-DNMT1-G9a-Snail1 complex.

Duvall-Noelle N, Karwandyar A, Richmond A, Raman D

Nuclear LASP-1 (LIM and SH3 protein-1) has a direct correlation with overall survival of breast cancer patients. In this study, immunohistochemical analysis of a human breast TMA showed that LASP-1 is absent in normal human breast epithelium but the expression increases with malignancy and is highly nuclear in aggressive breast cancer. We investigated whether the chemokines and growth factors present ... [more]

Oncogene Mar. 03, 2016; 35(9);1122-33 [Pubmed: 25982273]

Throughput

  • High Throughput

Curated By

  • BioGRID