BAIT
LASP1
Lasp-1, MLN50
LIM and SH3 protein 1
GO Process (2)
GO Function (3)
GO Component (3)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
AP3M1
RP11-178G16.4
adaptor-related protein complex 3, mu 1 subunit
GO Process (3)
GO Function (2)
GO Component (2)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
LASP-1: a nuclear hub for the UHRF1-DNMT1-G9a-Snail1 complex.
Nuclear LASP-1 (LIM and SH3 protein-1) has a direct correlation with overall survival of breast cancer patients. In this study, immunohistochemical analysis of a human breast TMA showed that LASP-1 is absent in normal human breast epithelium but the expression increases with malignancy and is highly nuclear in aggressive breast cancer. We investigated whether the chemokines and growth factors present ... [more]
Oncogene Mar. 03, 2016; 35(9);1122-33 [Pubmed: 25982273]
Throughput
- High Throughput
Curated By
- BioGRID