SED5
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
SFT2
Gene Ontology Biological Process
Gene Ontology Cellular Component
Phenotypic Suppression
A genetic interaction is inferred when mutation or over expression of one gene results in suppression of any phenotype (other than lethality/growth defect) associated with mutation or over expression of another gene.
Publication
The Roles of the SNARE Protein Sed5 in Autophagy in Saccharomyces cerevisiae.
Autophagy is a degradation pathway in eukaryotic cells in which aging proteins and organelles are sequestered into double-membrane vesicles, termed autophagosomes, which fuse with vacuoles to hydrolyze cargo. The key step in autophagy is the formation of autophagosomes, which requires different kinds of vesicles, including COPII vesicles and Atg9- containing vesicles, to transport lipid double-membranes to the phagophore assembly site ... [more]
Throughput
- Low Throughput
Ontology Terms
- phenotype: autophagy (APO:0000074)
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| SED5 SFT2 | Dosage Rescue Dosage Rescue A genetic interaction is inferred when over expression or increased dosage of one gene rescues the lethality or growth defect of a strain that is mutated or deleted for another gene. | Low | - | BioGRID | 162032 | |
| SFT2 SED5 | Synthetic Lethality Synthetic Lethality A genetic interaction is inferred when mutations or deletions in separate genes, each of which alone causes a minimal phenotype, result in lethality when combined in the same cell under a given condition. | Low | - | BioGRID | 158784 |
Curated By
- BioGRID