BAIT
TRIM29
1110047J21Rik, 2810431N19Rik, 4732461M22Rik, AI119726
tripartite motif-containing 29
GO Process (2)
GO Function (2)
GO Component (3)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
UBB
AL033289, Rps27a, Uba52, Ubb2, Ubc, RP23-234K24.1
ubiquitin B
GO Process (16)
GO Function (0)
GO Component (4)
Gene Ontology Biological Process
- adipose tissue development [IMP]
- energy homeostasis [IMP]
- fat pad development [IMP]
- female gonad development [IMP]
- female meiosis I [IMP]
- hypothalamus gonadotrophin-releasing hormone neuron development [IMP]
- male gonad development [IMP]
- male meiosis I [IMP]
- mitochondrion transport along microtubule [ISO]
- neuron projection morphogenesis [ISO]
- positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator [ISO]
- regulation of mitochondrial membrane potential [ISO]
- regulation of neuron death [ISO]
- regulation of proteasomal protein catabolic process [ISO]
- seminiferous tubule development [IMP]
- ubiquitin homeostasis [IGI, IMP]
Gene Ontology Cellular Component
Mus musculus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Identification of a role for TRIM29 in the control of innate immunity in the respiratory tract.
The respiratory tract is heavily populated with innate immune cells, but the mechanisms that control such cells are poorly defined. Here we found that the E3 ubiquitin ligase TRIM29 was a selective regulator of the activation of alveolar macrophages, the expression of type I interferons and the production of proinflammatory cytokines in the lungs. We found that deletion of TRIM29 ... [more]
Nat. Immunol. Dec. 01, 2016; 17(12);1373-1380 [Pubmed: 27695001]
Throughput
- High Throughput
Curated By
- BioGRID