BAIT

PTEN

10q23del, BZS, CWS1, DEC, GLM2, MHAM, MMAC1, PTEN1, TEP1
phosphatase and tensin homolog
GO Process (64)
GO Function (11)
GO Component (10)

Gene Ontology Biological Process

Homo sapiens

Affinity Capture-MS

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.

Publication

The tumour suppressor PTEN mediates a negative regulation of the E3 ubiquitin-protein ligase Nedd4.

Ahn Y, Hwang CY, Lee SR, Kwon KS, Lee C

The tumour suppressor PTEN (phosphatase and tensin homologue deleted on chromosome 10; a phosphatidylinositol 3-phosphatase) is a multifunctional protein deregulated in many types of cancer. It is suggested that a number of proteins that relate with PTEN functionally or physically have not yet been found. In order to search for PTEN-interacting proteins that might be crucial in the regulation of ... [more]

Biochem. J. Jun. 01, 2008; 412(2);331-8 [Pubmed: 18307411]

Throughput

  • High Throughput

Curated By

  • BioGRID