BAIT

G3BP1

G3BP, HDH-VIII
GTPase activating protein (SH3 domain) binding protein 1
GO Process (3)
GO Function (4)
GO Component (2)
Homo sapiens
PREY

HSPA9

CRP40, CSA, GRP-75, GRP75, HEL-S-124m, HSPA9B, MOT, MOT2, MTHSP75, PBP74
heat shock 70kDa protein 9 (mortalin)
Homo sapiens

Affinity Capture-MS

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.

Publication

ATPase-Modulated Stress Granules Contain a Diverse Proteome and Substructure.

Jain S, Wheeler JR, Walters RW, Agrawal A, Barsic A, Parker R

Stress granules are mRNA-protein granules that form when translation initiation is limited, and they are related to pathological granules in various neurodegenerative diseases. Super-resolution microscopy reveals stable substructures, referred to as cores, within stress granules that can be purified. Proteomic analysis of stress granule cores reveals a dense network of protein-protein interactions and links between stress granules and human diseases ... [more]

Cell Jan. 28, 2016; 164(3);487-98 [Pubmed: 26777405]

Throughput

  • High Throughput

Related interactions

InteractionExperimental Evidence CodeDatasetThroughputScoreCurated ByNotes
HSPA9 G3BP1
Co-fractionation
Co-fractionation

Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.

High0.2314BioGRID
1262322

Curated By

  • BioGRID