BAIT

G3BP1

G3BP, HDH-VIII
GTPase activating protein (SH3 domain) binding protein 1
GO Process (3)
GO Function (4)
GO Component (2)
Homo sapiens
PREY

TOMM34

HTOM34P, TOM34, URCC3
translocase of outer mitochondrial membrane 34
GO Process (1)
GO Function (1)
GO Component (6)

Gene Ontology Biological Process

Gene Ontology Molecular Function

Homo sapiens

Affinity Capture-MS

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.

Publication

ATPase-Modulated Stress Granules Contain a Diverse Proteome and Substructure.

Jain S, Wheeler JR, Walters RW, Agrawal A, Barsic A, Parker R

Stress granules are mRNA-protein granules that form when translation initiation is limited, and they are related to pathological granules in various neurodegenerative diseases. Super-resolution microscopy reveals stable substructures, referred to as cores, within stress granules that can be purified. Proteomic analysis of stress granule cores reveals a dense network of protein-protein interactions and links between stress granules and human diseases ... [more]

Cell Jan. 28, 2016; 164(3);487-98 [Pubmed: 26777405]

Throughput

  • High Throughput

Curated By

  • BioGRID