UBE2A
Gene Ontology Biological Process
- DNA repair [IGI]
- antigen processing and presentation of peptide antigen via MHC class I [TAS]
- histone H2A ubiquitination [IDA]
- positive regulation of cell proliferation [IDA]
- postreplication repair [NAS]
- proteasome-mediated ubiquitin-dependent protein catabolic process [IBA]
- protein K11-linked ubiquitination [IDA]
- protein K48-linked ubiquitination [IDA]
- protein autoubiquitination [IDA]
- protein polyubiquitination [TAS]
- response to UV [IGI]
- ubiquitin-dependent protein catabolic process [NAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
CD59
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Interactome Analysis Reveals a Novel Role for RAD6 in the Regulation of Proteasome Activity and Localization in Response to DNA Damage.
RAD6, an E2 ubiquitin-conjugating enzyme, is a key node for determining different DNA damage repair pathways, controlling both the error-prone and the error-free DNA damage repair pathways through differential regulation of the ubiquitination of the proliferating cell nuclear antigen (PCNA) protein. However, whether other pathways are involved in the RAD6-mediated regulation of DNA damage repair is still unclear. To deeply ... [more]
Throughput
- High Throughput
Additional Notes
- Source of UBE2A not clear
Related interactions
Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
---|---|---|---|---|---|---|
UBE2A CD59 | Affinity Capture-MS Affinity Capture-MS An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods. | High | - | BioGRID | 1443596 |
Curated By
- BioGRID