BAIT

FAM107A

DRR1, TU3A
family with sequence similarity 107, member A
GO Process (1)
GO Function (0)
GO Component (1)

Gene Ontology Biological Process

Gene Ontology Cellular Component

Homo sapiens
PREY

AUH

AU RNA binding protein/enoyl-CoA hydratase
Homo sapiens

Two-hybrid

Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.

Publication

A novel nuclear complex of DRR1, F-actin and COMMD1 involved in NF-κB degradation and cell growth suppression in neuroblastoma.

Mu P, Akashi T, Lu F, Kishida S, Kadomatsu K

Downregulated in renal cell carcinoma 1 (DRR1) has important roles in tumor cell growth, neuron survival and spine formation, and was recently shown to bind actin. However, the roles of nuclear DRR1 remain largely unexplored. Here, we identified an interaction between filamentous actin (F-actin) and DRR1 in the nucleus, and demonstrated that copper metabolism MURR1 domain-containing 1 (COMMD1) is another ... [more]

Oncogene Oct. 12, 2017; 36(41);5745-5756 [Pubmed: 28604741]

Throughput

  • Low Throughput

Curated By

  • BioGRID