BAIT
PCBP1
HEL-S-85, HNRPE1, HNRPX, hnRNP-E1, hnRNP-X
poly(rC) binding protein 1
GO Process (3)
GO Function (4)
GO Component (5)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
FOXN2
HTLF
forkhead box N2
GO Process (0)
GO Function (0)
GO Component (3)
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Poly r(C) binding protein (PCBP) 1 expression is regulated by the E3 ligase UBE4A in thyroid carcinoma.
Thyroid cancer patients with high miR-490-3p inhibit translation ofPCBP1mRNA, whereas in patients with low miR-490-3pPCBP1mRNA expression is high; however, the resultant protein is targeted for degradation through the proteasome. The objective of the present study was to evaluate the molecular mechanism that regulates post-translation degradation of poly r(C) binding protein (PCBP) 1 expression in thyroid cancer cells. Mass spectrometric analysis ... [more]
Biosci. Rep. Oct. 31, 2017; 37(5); [Pubmed: 28963376]
Throughput
- Low Throughput
Curated By
- BioGRID