BAIT

TES

TESS, TESS-2
testis derived transcript (3 LIM domains)
GO Process (1)
GO Function (2)
GO Component (6)

Gene Ontology Biological Process

Gene Ontology Molecular Function

Gene Ontology Cellular Component

Homo sapiens
PREY

SACM1L

SAC1
SAC1 suppressor of actin mutations 1-like (yeast)
GO Process (3)
GO Function (2)
GO Component (3)

Gene Ontology Biological Process

Gene Ontology Molecular Function

Gene Ontology Cellular Component

Homo sapiens

Affinity Capture-MS

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.

Publication

Expanding the Interactome of TES by Exploiting TES Modules with Different Subcellular Localizations.

Sala S, Van Troys M, Medves S, Catillon M, Timmerman E, Staes A, Schaffner-Reckinger E, Gevaert K, Ampe C

The multimodular nature of many eukaryotic proteins underlies their temporal or spatial engagement in a range of protein cocomplexes. Using the multimodule protein testin (TES), we here report a proteomics approach to increase insight in cocomplex diversity. The LIM-domain containing and tumor suppressor protein TES is present at different actin cytoskeleton adhesion structures in cells and influences cell migration, adhesion ... [more]

J. Proteome Res. May. 05, 2017; 16(5);2054-2071 [Pubmed: 28378594]

Throughput

  • High Throughput

Additional Notes

  • amino acids 1-421 of testin (full length protein) were used as bait

Curated By

  • BioGRID