BAIT
TES
TESS, TESS-2
testis derived transcript (3 LIM domains)
GO Process (1)
GO Function (2)
GO Component (6)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
MACF1
ABP620, ACF7, MACF, OFC4
microtubule-actin crosslinking factor 1
GO Process (8)
GO Function (5)
GO Component (6)
Gene Ontology Biological Process
- ATP catabolic process [ISS]
- Golgi to plasma membrane protein transport [IDA]
- positive regulation of Wnt signaling pathway [ISS]
- positive regulation of axon extension [IDA]
- regulation of epithelial cell migration [ISS]
- regulation of focal adhesion assembly [ISS]
- regulation of microtubule-based process [IMP]
- wound healing [ISS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Expanding the Interactome of TES by Exploiting TES Modules with Different Subcellular Localizations.
The multimodular nature of many eukaryotic proteins underlies their temporal or spatial engagement in a range of protein cocomplexes. Using the multimodule protein testin (TES), we here report a proteomics approach to increase insight in cocomplex diversity. The LIM-domain containing and tumor suppressor protein TES is present at different actin cytoskeleton adhesion structures in cells and influences cell migration, adhesion ... [more]
J. Proteome Res. May. 05, 2017; 16(5);2054-2071 [Pubmed: 28378594]
Throughput
- High Throughput
Additional Notes
- amino acids 92-199 of testin (PET domain) were used as bait
Curated By
- BioGRID