BAIT
ORF21
HHV8GK18_gp25
thymidine kinase
GO Process (0)
GO Function (0)
GO Component (0)
Human Herpesvirus 8
PREY
PAIP1
poly(A) binding protein interacting protein 1
GO Process (8)
GO Function (2)
GO Component (2)
Gene Ontology Biological Process
- RNA metabolic process [TAS]
- gene expression [TAS]
- mRNA metabolic process [TAS]
- mRNA stabilization [TAS]
- nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [TAS]
- nuclear-transcribed mRNA poly(A) tail shortening [TAS]
- positive regulation of translation [IDA]
- translational initiation [TAS]
Gene Ontology Molecular Function
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Global mapping of herpesvirus-host protein complexes reveals a transcription strategy for late genes.
Mapping host-pathogen interactions has proven instrumental for understanding how viruses manipulate host machinery and how numerous cellular processes are regulated. DNA viruses such as herpesviruses have relatively large coding capacity and thus can target an extensive network of cellular proteins. To identify the host proteins hijacked by this pathogen, we systematically affinity tagged and purified all 89 proteins of Kaposi's ... [more]
Mol. Cell Jan. 22, 2015; 57(2);349-60 [Pubmed: 25544563]
Throughput
- High Throughput
Curated By
- BioGRID