PRKAA1
Gene Ontology Biological Process
- cellular response to glucose starvation [IDA]
- cellular response to nutrient levels [IDA]
- cellular response to prostaglandin E stimulus [IGI]
- cold acclimation [ISO]
- fatty acid homeostasis [ISO]
- fatty acid oxidation [IMP]
- glucose homeostasis [IMP]
- glucose metabolic process [IMP]
- histone-serine phosphorylation [IDA]
- lipid biosynthetic process [IDA]
- negative regulation of TOR signaling [IMP]
- negative regulation of apoptotic process [IMP]
- negative regulation of glucose import in response to insulin stimulus [ISO]
- negative regulation of lipid catabolic process [IDA]
- positive regulation of autophagy [IMP]
- positive regulation of cell proliferation [ISO]
- positive regulation of gene expression [ISO]
- positive regulation of glycolytic process [ISO]
- protein heterooligomerization [ISO]
- protein phosphorylation [IMP, ISO]
- regulation of circadian rhythm [IMP]
- regulation of energy homeostasis [ISO]
- regulation of vesicle-mediated transport [ISO]
- response to UV [IMP]
- response to activity [ISO]
- response to caffeine [ISO]
- response to camptothecin [IMP]
- response to gamma radiation [IMP]
- response to hydrogen peroxide [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
CYCS
Gene Ontology Biological Process
- activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c [IMP]
- apoptotic DNA fragmentation [ISO]
- apoptotic process [IDA]
- hydrogen peroxide metabolic process [IDA]
- mitochondrial electron transport, cytochrome c to oxygen [IBA]
- mitochondrial electron transport, ubiquinol to cytochrome c [IBA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Affinity Capture-Western
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins.
Publication
Phosphorylation of Cytochrome c Threonine 28 Regulates Electron Transport Chain Activity in Kidney: IMPLICATIONS FOR AMP KINASE.
Mammalian cytochrome c (Cytc) plays a key role in cellular life and death decisions, functioning as an electron carrier in the electron transport chain and as a trigger of apoptosis when released from the mitochondria. However, its regulation is not well understood. We show that the major fraction of Cytc isolated from kidneys is phosphorylated on Thr28, leading to a ... [more]
Throughput
- Low Throughput
Curated By
- BioGRID