BAIT
MAP1LC3A
ATG8E, LC3, LC3A, MAP1ALC3, MAP1BLC3, RP11-346K17.1
microtubule-associated protein 1 light chain 3 alpha
GO Process (5)
GO Function (5)
GO Component (6)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
LMNB1
ADLD, LMN, LMN2, LMNB
lamin B1
GO Process (2)
GO Function (0)
GO Component (4)
Gene Ontology Biological Process
Gene Ontology Cellular Component
Homo sapiens
Reconstituted Complex
An interaction is detected between purified proteins in vitro.
Publication
Autophagy mediates degradation of nuclear lamina.
Macroautophagy (hereafter referred to as autophagy) is a catabolic membrane trafficking process that degrades a variety of cellular constituents and is associated with human diseases. Although extensive studies have focused on autophagic turnover of cytoplasmic materials, little is known about the role of autophagy in degrading nuclear components. Here we report that the autophagy machinery mediates degradation of nuclear lamina ... [more]
Nature Nov. 05, 2015; 527(7576);105-9 [Pubmed: 26524528]
Throughput
- Low Throughput
Curated By
- BioGRID