MCM9
Gene Ontology Biological Process
Gene Ontology Cellular Component
HORMAD1
Gene Ontology Biological Process
- blastocyst development [ISS]
- meiotic DNA double-strand break formation [ISS]
- meiotic nuclear division [ISS]
- meiotic recombination checkpoint [ISS]
- meiotic sister chromatid cohesion [ISS]
- oogenesis [ISS]
- regulation of homologous chromosome segregation [ISS]
- spermatogenesis [ISS]
- synaptonemal complex assembly [ISS]
Gene Ontology Cellular Component
- chromosome [ISS]
- nucleus [IDA]
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
MCM9 Is Required for Mammalian DNA Mismatch Repair.
DNA mismatch repair (MMR) is an evolutionarily conserved process that corrects DNA polymerase errors during replication to maintain genomic integrity. In E. coli, the DNA helicase UvrD is implicated in MMR, yet an analogous helicase activity has not been identified in eukaryotes. Here, we show that mammalian MCM9, a protein involved in replication and homologous recombination, forms a complex with ... [more]
Throughput
- Low Throughput
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| MCM9 HORMAD1 | Affinity Capture-MS Affinity Capture-MS An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods. | Low | - | BioGRID | - |
Curated By
- BioGRID