BAIT
HOMER1
HOMER, HOMER1A, HOMER1B, HOMER1C, SYN47, Ves-1
homer homolog 1 (Drosophila)
GO Process (6)
GO Function (3)
GO Component (1)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
HOMER1
HOMER, HOMER1A, HOMER1B, HOMER1C, SYN47, Ves-1
homer homolog 1 (Drosophila)
GO Process (6)
GO Function (3)
GO Component (1)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Reconstituted Complex
An interaction is detected between purified proteins in vitro.
Publication
Homer protein increases activation of Ca2+ sparks in permeabilized skeletal muscle.
Members of the Homer family of proteins are known to form multimeric complexes capable of cross-linking plasma membrane channels (e.g. metabotropic glutamate receptor) and intracellular Ca2+ release channels (e.g. inositol trisphosphate receptor) in neurons, which potentiates Ca2+ release. Recent work has demonstrated direct interaction of Homer proteins with type 1 and type 2 ryanodine receptor (RyR) isoforms. Moreover, Homer proteins ... [more]
J. Biol. Chem. Feb. 13, 2004; 279(7);5781-7 [Pubmed: 14660561]
Throughput
- Low Throughput
Curated By
- BioGRID