BAIT
TCERG1
CA150, TAF2S, Urn1
transcription elongation regulator 1
GO Process (2)
GO Function (5)
GO Component (3)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Homo sapiens
PREY
TPM4
HEL-S-108
tropomyosin 4
GO Process (4)
GO Function (2)
GO Component (7)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
The WW domain-containing proteins interact with the early spliceosome and participate in pre-mRNA splicing in vivo.
A growing body of evidence supports the coordination of mRNA synthesis and its subsequent processing events. Nuclear proteins harboring both WW and FF protein interaction modules bind to splicing factors as well as RNA polymerase II and may serve to link transcription with splicing. To understand how WW domains coordinate the assembly of splicing complexes, we used glutathione S-transferase fusions ... [more]
Mol. Cell. Biol. Oct. 01, 2004; 24(20);9176-85 [Pubmed: 15456888]
Throughput
- Low Throughput
Curated By
- BioGRID