BAIT
NEK6
SID6-1512, RP11-101K10.6
NIMA-related kinase 6
GO Process (14)
GO Function (7)
GO Component (3)
Gene Ontology Biological Process
- G2 DNA damage checkpoint [IMP]
- chromosome segregation [IDA]
- cytokinesis [TAS]
- mitotic cell cycle [TAS]
- mitotic nuclear envelope disassembly [TAS]
- peptidyl-serine phosphorylation [IDA]
- positive regulation of I-kappaB kinase/NF-kappaB signaling [IMP]
- protein autophosphorylation [IDA]
- protein phosphorylation [IDA]
- regulation of cellular senescence [TAS]
- regulation of mitotic cell cycle [TAS]
- regulation of mitotic metaphase/anaphase transition [IDA]
- signal transduction [IMP]
- spindle assembly [TAS]
Gene Ontology Molecular Function
Homo sapiens
PREY
LRPPRC
CLONE-23970, GP130, LRP130, LSFC
leucine-rich pentatricopeptide repeat containing
GO Process (1)
GO Function (6)
GO Component (8)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Large-scale mapping of human protein-protein interactions by mass spectrometry.
Mapping protein-protein interactions is an invaluable tool for understanding protein function. Here, we report the first large-scale study of protein-protein interactions in human cells using a mass spectrometry-based approach. The study maps protein interactions for 338 bait proteins that were selected based on known or suspected disease and functional associations. Large-scale immunoprecipitation of Flag-tagged versions of these proteins followed by ... [more]
Mol. Syst. Biol. Mar. 14, 2007; 3(0);89 [Pubmed: 17353931]
Quantitative Score
- 0.39 [Confidence Score]
Throughput
- High Throughput
Ontology Terms
- cell line: hek-293 cell (BTO:0000007)
Additional Notes
- Exogenous expression of bait
Curated By
- BioGRID