BAIT
AP1S1
AP19, CLAPS1, EKV3, MEDNIK, SIGMA1A
adaptor-related protein complex 1, sigma 1 subunit
GO Process (7)
GO Function (0)
GO Component (8)
Gene Ontology Biological Process
Gene Ontology Cellular Component
Homo sapiens
PREY
SLC16A1
HHF7, MCT, MCT1, MCT1D, RP4-580L15.1
solute carrier family 16 (monocarboxylate transporter), member 1
GO Process (10)
GO Function (3)
GO Component (6)
Gene Ontology Biological Process
- blood coagulation [TAS]
- cellular metabolic process [TAS]
- centrosome organization [IMP]
- leukocyte migration [TAS]
- mevalonate transport [TAS]
- monocarboxylic acid transport [TAS]
- plasma membrane lactate transport [IBA, ISS]
- pyruvate metabolic process [TAS]
- small molecule metabolic process [TAS]
- transmembrane transport [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Large-scale mapping of human protein-protein interactions by mass spectrometry.
Mapping protein-protein interactions is an invaluable tool for understanding protein function. Here, we report the first large-scale study of protein-protein interactions in human cells using a mass spectrometry-based approach. The study maps protein interactions for 338 bait proteins that were selected based on known or suspected disease and functional associations. Large-scale immunoprecipitation of Flag-tagged versions of these proteins followed by ... [more]
Mol. Syst. Biol. Mar. 14, 2007; 3(0);89 [Pubmed: 17353931]
Quantitative Score
- 0.365 [Confidence Score]
Throughput
- High Throughput
Ontology Terms
- cell line: hek-293 cell (BTO:0000007)
Additional Notes
- Exogenous expression of bait
Curated By
- BioGRID