BAIT
CD2BP2
FWP010, LIN1, PPP1R59, Snu40, U5-52K
CD2 (cytoplasmic tail) binding protein 2
GO Process (5)
GO Function (2)
GO Component (6)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
CREBRF
C5orf41, LRF
CREB3 regulatory factor
GO Process (6)
GO Function (1)
GO Component (2)
Gene Ontology Biological Process
- negative regulation of endoplasmic reticulum unfolded protein response [IDA]
- negative regulation of transcription from RNA polymerase II promoter [IDA]
- positive regulation of intracellular transport [IDA]
- positive regulation of protein catabolic process [IDA]
- positive regulation of protein transport [IDA]
- response to endoplasmic reticulum stress [IDA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Large-scale mapping of human protein-protein interactions by mass spectrometry.
Mapping protein-protein interactions is an invaluable tool for understanding protein function. Here, we report the first large-scale study of protein-protein interactions in human cells using a mass spectrometry-based approach. The study maps protein interactions for 338 bait proteins that were selected based on known or suspected disease and functional associations. Large-scale immunoprecipitation of Flag-tagged versions of these proteins followed by ... [more]
Mol. Syst. Biol. Mar. 14, 2007; 3(0);89 [Pubmed: 17353931]
Quantitative Score
- 0.324 [Confidence Score]
Throughput
- High Throughput
Ontology Terms
- cell line: hek-293 cell (BTO:0000007)
Additional Notes
- Exogenous expression of bait
Curated By
- BioGRID